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Objective
Along with rapid economic growth, the United Arab Emirates (UAE) has undergone enormous sociocultural changes. Consequently, sociocultural and psychological factors, along with malnutrition and physical inactivity, have contributed to the high obesity rate. The objective of this study is to assess the long‐term impact of these new emerging factors on obesity among women in the UAE via mathematical...
Objective
The aim of this study was to examine COVID‐19 pandemic‐related changes in obesity and BMI among patients aged 5 to <20 years with selected chronic conditions.
Methods
A longitudinal study in 293,341 patients aged 5 to <20 years who were prescribed one of five medication classes (for depression, psychosis, hypertension, diabetes, or epilepsy) and who had BMI measures from January...
Objective
There have been conflicting reports concerning weight gain among adults during the COVID‐19 epidemic. Although early studies reported large weight increases, several of these analyses were based on convenience samples or self‐reported information. The objective of the current study is to examine the pandemic‐related weight increase associated with the pandemic through May 2021.
Methods...
Objective
The study aimed to identify BMI‐related lipids and to explore the role of lipids linking BMI and gestational diabetes mellitus (GDM).
Methods
Plasma lipidome, height, and weight were measured in early pregnancy among 1008 women. Pearson correlation analyses and least absolute shrinkage and selection operator regression (LASSO) were performed to identify BMI‐associated lipids. Based on...
Objective
Myeloid cells dominate metabolic disease‐associated inflammation (metaflammation) in mouse obesity, but the contributions of myeloid cells to the peripheral inflammation that fuels sequelae of human obesity are untested. This study used unbiased approaches to rank contributions of myeloid and T cells to peripheral inflammation in people with obesity across the spectrum of metabolic health...
Objective
This trial evaluated a smartphone application's effectiveness in improving adherence to vitamin and mineral supplementation postoperatively.
Methods
This study was a randomized controlled trial comprising 140 patients undergoing bariatric surgery (gastric bypass or sleeve gastrectomy). Participants were randomized 1:1 to the 12‐week intervention, using the smartphone application PromMera,...
Sixty years ago, the geneticist James Neel proposed that the epidemics of obesity and diabetes today may have evolutionary roots. Specifically, he suggested that our ancestors may have accumulated mutations during periods of famine that provided a survival advantage at that time. However, the presence of this “thrifty genotype” in today's world, where food is plentiful, would predispose us to obesity...
Objective
Reduced dorsolateral prefrontal cortex (dlPFC) activity and inhibitory control may contribute to obesity. The study objective was to assess effects of repeated transcranial direct current stimulation (tDCS) on food Go/No‐Go (GNG), food Stroop performance, and snack food intake.
Methods
Twenty‐nine individuals with obesity (12 male; mean [SD], age 42 [11] years; BMI 39 [8]) participated...
Objective
This study aimed to assess the association of BMI with inpatient care cost, duration, and acute complications among patients hospitalized for COVID‐19 at 273 US hospitals.
Methods
Children (aged 2–17 years) and adults (aged ≥18 years) hospitalized for COVID‐19 during March 2020–July 2021 and with measured BMI in a large electronic administrative health care database were included. Generalized...
Objective
Obesity is a major risk factor for severe disease in COVID‐19, with increased hospitalization, intensive care unit admission, and mortality. This increased impact of COVID‐19 in people with obesity (PWO) is likely driven, in part, by the well‐described obesity‐induced immune dysregulation. Obesity has also been associated with impaired immune memory in many settings, including weakened...
Objective
Weight history and its association with the weight loss achieved in a publicly funded clinical obesity management program were examined in 9348 patients.
Methods
Weight history (frequency and magnitude of weight losses) was collected through questionnaires at enrollment, and weight change was assessed with retrospective electronic medical chart review.
Results
The majority of patients...
Objective
This study aimed to investigate the association between low muscle mass or sarcopenic obesity and the risk of incident chronic kidney disease (CKD) in patients with type 2 diabetes mellitus (T2DM).
Methods
A total of 3123 patients with T2DM with preserved renal function were followed up for incident CKD. Skeletal muscle mass was estimated from bioelectrical impedance analysis. CKD was...
Objective
Despite military fitness regulations, women in the military frequently experience overweight/obesity, excessive gestational weight gain (GWG), and the postpartum implications. This interim analysis of the Moms Fit 2 Fight study examines GWG outcomes among active‐duty personnel and other TRICARE beneficiaries who received a stepped‐care GWG intervention compared with those who did not receive...
Objective
This study prospectively examined change in waist circumference (WC) as a function of daily social rhythms and sleep in the aftermath of involuntary job loss. It was hypothesized that disrupted social rhythms and fragmented/short sleep after job loss would independently predict gains in WC over 18 months and that resiliency to WC gain would be conferred by the converse.
Methods
Eligible...
Sleep is an ancient and evolutionarily conserved biological process that, when disturbed, increases the risk for a variety of diseases in people, including diabetes, cardiovascular disease, kidney disease, and cancer. Although results from epidemiological studies support the link between insufficient sleep and an increased risk of obesity, the directionality of this link is unknown. Results from short‐term...
Objective
The aim of this study was to compare changes in hedonic hunger and food reward in individuals with severe obesity achieving 10% to 15% weight loss with a very low‐energy diet (VLED) alone or VLED and bariatric surgery.
Methods
Patients scheduled for sleeve gastrectomy (SG) or Roux‐en‐Y gastric bypass (RYGB) initiated a VLED 2 weeks prior to surgery and continued the diet for 8 weeks postoperatively...
Objective
Obesity increases the risk for pregnancy complications and maternal hyperglycemia. The Institute of Medicine developed guidelines for gestational weight gain (GWG) targets for women with overweight/obesity, but it is unclear whether exceeding these targets has adverse effects on maternal glucose metabolism.
Methods
Insulin sensitivity (assessed using the Matsuda Insulin Sensitivity Index),...
Objective
The study goal was to analyze the effects of a high‐fat diet (HFD) on the histone 3 lysine 27 (H3K27) posttranscriptional modifications and the expression of histone‐modifying enzymes in adipose‐derived stromal cells (ASCs) from white adipose tissue (WAT).
Methods
Male C57BL/6J mice received control or HFD for 12 weeks. The ASCs were isolated from subcutaneous and visceral (epididymal)...
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